As a Multiple Sclerosis patient, it has become necessary for me to reinvent myself. I have ... and continue to ... refuse to lie down and die, or in this case, follow the normally prescribed drugs and treatments that do nothing to defeat my disease. I am not only surviving by pursuing alternatives, I am thriving. I do the things specialists told me I would never be able to do. I walk and hope to one day even run regularly. I retain my cognitive and creative abilities for the pleasure of my readers. Although you may never see me on my daily walk, you are welcome to read my novel(s) and in doing so, come to ask yourself, "How can the 'out of the box' protocol she has followed, help my loved one with an autoimmune disease like Multiple Sclerosis?"

Push Her Off the Roof: Escalating the Stakes

Melanie started out with having us draw a picture of our character. Then give the character what he or she wants.
We actually drew pictures.
Then we hurt our character and drew why we did it. Then discussed the feelings that came after.
All of this was to make sure we gave our character a big enough goal or conflict that changed them. And basically rip the rug out from under them, but with a good reason. So she talked about how to engage the reader in the character's plight. The reader will employ empathy while they're reading.
Painting a sad picture first and then giving them something happy releases the dopamine. Happiness after the pain registers strongly with the reader as though they're experiencing it.
Small hurts are bumps, bruises, etc. or inconveniences. Bigger hurts will move the story along but they don't change the arc of the novel. Transformational hurts make profound changes to the character permanently and change the story. i.e. A football player is so injured that he can't ever play ever again. He's paralyzed.
A guy's hand is cut off by the queen and he can't do his occupation anymore. She begins to regret her actions and changes. He changes as well and grows into the person he now is. (by the end of the story.) There are multiple types of hurt to employ in your story. Physical, emotional and sense of justice.
In every culture there is a sense of fair and what is not; and a deep sense of justice arises. Small can be name calling and that equals emotional hurt. Bigger level might be a break up. Also emotional hurt, but bigger. Transformational emotional hurt might be a divorce.
Physical transformation is loss of limb, cancer, brain injury. Complications have to MATTER
Does the reader want to get riled up with a sense of injustice? Is this a good way to engage the reader? Give characters something to love, relatable goals, and a powerful want
I think if you take the reader on the journey, then yes, have them care about the injustice and want it remedied. I think injustice is a great one. Like Scrooge brushing off Tiny Tim

I would write it so differently if I'm trying to build up a sense of injustice in the reader, than if I'm trying to engender sympathy from the reader. 
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